Important note: sig-up for NURSING (VPK) and CHEMISTRY (C) students use Bisoncode: L.26145
Important note: sign-up for BIOMEDICAL & LABORATORY RESEARCH (BML) students use Bisoncode: L.26329

 

In this project you will be contributing to the development of a portable insulin sensor to detect development towards diagnosis in a very early stage. When ready, this device can be used by anybody who wants to determine whether he/she is developing diabetes (typically 3 to 5 years before diagnosed clinically as diabetes) and needs to adapt their lifestyle (diet, exercise) to avoid getting diabetes. 

Half of the Dutch population over the age of 18 is overweight or overweight, obese. The main cause is a diet with a lot of sugar, such as in soft drinks and fruit drinks, and too many carbohydrates, such as bread, white rice and spaghetti. Carbohydrates are converted into glucose, a source of energy. However, if we eat more sugars and carbohydrates than we need, our liver converts this into fat, which can cause inflammation and, in the long run, diabetes, heart attack, stroke, cancer and even dementia.  

The degree of fat formation is not the same for everyone. Some people can process carbohydrates and glucose well, but 70% of people cannot. The most important factor is insulin, a hormone that controls the absorption of glucose. If you make too much, you are constantly hungry and eat too much; make too little, too much glucose remains in your blood that damages blood vessels and makes tumors grow. The first indication of severely damaged blood vessels is a heart attack or stroke. By measuring both glucose and insulin, you can determine whether your diet is not harmful to your body, whether you are on your way to diabetes, or already have type 2 diabetes. 

The question is whether it is possible to develop an affordable sensor based on existing technologies that can measure insulin and glucose in human blood quickly, easily to operate, accurately and specifically at clinically relevant concentrations. Saxion, in collaboration with the University of Twente, a number of high-tech SMEs and social partners, will develop the knowledge to realize this sensor based on optically integrated photonic chips. With this knowledge, a demonstrator is developed and tested with realistic blood samples. In addition, it will be investigated how this sensor can be used in practice for screening people in order to detect diabetes at a very early stage.  

In this project you will be contributing to the development of a portable insulin sensor to detect development towards diagnosis in a very early stage. When ready, this device can be used by anybody who wants to determine whether he/she is developing diabetes (typically 3 to 5 years before diagnosed clinically as diabetes) and needs to adapt their lifestyle (diet, exercise) to avoid getting diabetes.

Required study programs: 

Biology & Laboratory Research (BML): Develop a handheld device for measuring insulin. Detecting proteins with insulin.

Chemistry (C): Develop a handheld device for measuring insulin.

Nursing (VPK): Application is in the healthcare for which we need to do some fieldwork.

Location: Saxion UAS, Enschede or Deventer

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Questions about this project?

Feel free to contact us if you have any questions about this project. You can call us at 088 - 019 53 11 or use the form below. We wil get back to you within two business days.